RBA IVF success

PATIENT’S OWN EGGS
Final Cumulative Outcome Per Egg Retrieval Cycle

2016 (Preliminary Data)
RBA IVF Stats Summary
<35 35­-37 38­-40 41­-42 >42
Number of Cycle Starts 271 138 133 43 25
Singletons 44.3% 31.2% 22.6% 18.6% 4%
Twins 4.4% 3.6% 2.3% 7% 0%
Triplets or more 0% 0% 0% 0% 0%
Live Births 48.7% 34.8% 24.8% 25.6% 4%
Confidence Range (42.8 – 54.7) (26.8 – 42.7) (17.5 – 32.2) (12.5 – 38.6) (0 – 11.7)
Term 84.1% 81.2% 75.8% 9/11 1/1
Pre-term 13.6% 16.7% 21.2% 2/11 0/1
Very pre-term 2.3 2.1% 3.0% 0/11 0/1

PATIENT’S OWN EGGS
Preliminary Live Birth Per New Patient

2016 (Preliminary Data)
RBA IVF Stats Summary
<35 35­-37 38­-40 41­-42 >42
Number of Cycle Starts 225 93 85 26 15
Singletons 50.2% 38.7% 29.4% 23.1% 1/15
Twins 4.9% 5.4% 2.4% 3.8% 0/15
Triplets or more 0% 0% 0% 0% 0/15
Live Births 55.1% 44.1% 31.8% 26.9% 1/15
Confidence Range (48.6 – 61.6) (34.0 – 54.2) (21.9 – 41.7) (9.9 – 44.0)
Term 83.9% 78.0% 74.1% 7/7 1/1
Pre-term 14.5% 19.5% 22.2% 0/7 0/1
Very pre-term 1.6% 2.4% 3.7% 0/7 0/1

Understanding Clinic Pregnancy Statistics

IVF clinics have been required by federal law to report pregnancy outcomes to the Centers for Disease Control (CDC) since the 1990’s. Until very recently, multiple flaws in the rules governing the reporting of these statistics allowed clinics to artificially inflate pregnancy rates. Beginning with the 2014 data set, published in Spring 2016, clinics are now required to report outcomes by a new set of rules. The new rules limit a clinic’s ability to manipulate statistics and will lead to complete accounting of all IVF attempts in any given center.

The new data tables contain much more information than in the past, but reward clinics for encouraging single embryo transfer by showing the preliminary chance of pregnancy in a fresh cycle and then adding to the cumulative pregnancy rate by showing the subsequent rate of live birth for each additional transfer of frozen embryos arising from the same initial egg retrieval. Patients will also see a ‘live birth per patient’ statistic, which gives patients the best overall idea of what they can expect when they initiate care in an IVF center.

The new reporting rules are a significant improvement over the previous set of requirements but still lack a few key points that will matter to patients. First among these missing data points is the impact of genetic screening on embryos and second is the overall cost to a patient per live birth. Clinics that rely heavily on genetic screening will show higher pregnancy rates per embryo transfer but lower pregnancy rates per attempt. Over time it is likely that the top 100 clinics or so will have comparable rates per patient, but clinics that apply genetic screening selectively will probably show lower overall cost per baby born than clinics that test everyone. Ultimately, patients will be able to evaluate a clinic not only on its published pregnancy rates but also on the efficiency of a clinic’s patient care and will determine where to seek treatment based on factors other than the numbers.

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